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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of cataract
ncRNA name ALDH1A1 siRNA
ncRNA Category siRNA
Disease name cataract
Species Rattus norvegicus
Tissues/Cell_line lenses
Methods siRNA transfection, RT-PCR, ELISA, HPLC analysis, gas chromatography, chemical ionization-mass spectrometry
Expression pattern associated
Functional description The metabolism of 3H-HNE was studied in ALDH3A1-knockout mouse lens and in HLECs transfected with ALDH1A1- or -3A1-specific antisense RNA and short interfering (Si)RNA.
PubMed ID 15623782
Year 2005
Title Role of aldehyde dehydrogenase isozymes in the defense of rat lens and human lens epithelial cells against oxidative stress.
Drug-related ncRNA NO

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